延续前一集的剧情，狮子亚历克斯（本·斯蒂勒 Ben Stiller 配音）、斑马马蒂（克里斯·洛克 Chris Rock 配音）、长颈鹿迈尔曼（大卫·休默 David Schwimmer 配音）、河马格洛里亚（贾达·萍克·史密斯 Jada Pinkett Smith 配音）以及企鹅们，为了能离开马达加斯加岛回到五光十色的纽约，对一架破旧的失事飞机进行维修改造...
Henry is an introverted architect. After the death of his wife in a car accident, he sets out to help Millie, a homeless teen, to build a raft to sail across the Atlantic.
With his alimony spent on his younger wife Gloria, Vince’s former wife Ellen moves back in with son Mark. While a diner waitress dates Mark and takes advantage of Vince, Ellen hopes getting over Vince by dating his lawyer Jerry.
